Coffee with Artemisia annua Extract

Coffee infused with Artemisia annua extract, obtained through subcritical extraction, is an innovative beverage that combines the stimulating properties of coffee with the powerful medicinal benefits of sweet wormwood. This method preserves the maximum amount of bioactive compounds, ensuring high effectiveness and health benefits.

Active Ingredients in Artemisia annua Extract

The extract contains a high concentration of terpenes and other active substances:
•	Terpenes:
•	β-Caryophyllene – 1.68% (anti-inflammatory, analgesic, antioxidant properties) 
•	γ-Terpinene – 3.46% (antioxidant, immune support) 
•	α-Pinene – 0.48% (bronchodilator, anti-inflammatory) 
•	Eucalyptol – 0.67% (antiseptic, mucolytic) 
•	α-Humulene – 0.95% (anti-inflammatory, antibacterial) 
•	Camphor – 0.13% (stimulating effect on the nervous system) 
•	Guaiol – 0.19% (antiseptic, anti-inflammatory) 
•	α-Bisabolol – 0.14% (soothing and regenerative effect) 
•	γ-Terpineol – 0.49% (antioxidant, immune-modulating properties) 
•	Other Active Compounds:
•	Artemisinin – known for its anti-malarial, anti-cancer, and immune-modulating effects. 
•	Flavonoids – quercetin, luteolin, and kaempferol provide antioxidant, anti-inflammatory, and neuroprotective benefits. 
•	Polysaccharides – strengthen the immune system and promote detoxification. 

Synergistic Effects of Artemisia annua Extract and Coffee

The combination of Artemisia annua extract with coffee significantly enhances its health benefits:
•	Caffeine – a natural stimulant that boosts mental focus and physical endurance while enhancing the anti-inflammatory effects of terpenes. 
•	Chlorogenic Acid – an antioxidant that protects cells from oxidative stress. 
•	Trigonelline – stimulates nerve cell regeneration and provides neuroprotective effects. 
•	Caffeic Acid – has anti-cancer properties and supports metabolic function. 
Herbal essence

Target Groups that May Benefit from This Beverage

1.	People with Chronic Inflammatory Diseases
In 2023, the number of people with arthritis, asthma, and other chronic inflammatory diseases in the U.S. reached a record high in the past 33 years (GXPNews). The anti-inflammatory properties of Artemisia annua extract, including β-Caryophyllene and α-Pinene, can help reduce inflammation and alleviate symptoms.
2.	People with Cardiovascular Diseases
With the increasing prevalence of cardiovascular diseases in the U.S., coffee with Artemisia annua extract can contribute to heart health through its antioxidant and vasodilatory effects.
3.	People at Risk of Viral Infections
As of February 2025, more than 111 million COVID-19 cases have been reported in the U.S. (NCOV Online). The antiviral activity of Artemisia annua extract may help strengthen the immune system and reduce the risk of infections.
4.	Cancer Patients
Artemisinin has demonstrated anti-cancer properties (Onco.Rehab), making this beverage a potential complementary aid for patients undergoing cancer treatment.
5.	People with Diabetes
Artemisia annua extract has been found to help lower blood sugar levels (Ataman Chemicals).

Conclusion

Coffee with Artemisia annua extract is an innovative functional beverage that merges the stimulating effects of coffee with the powerful therapeutic benefits of natural plant compounds. With proven synergistic effects, this drink can support immune function, protect against viral infections, aid in inflammatory and cardiovascular conditions, and serve as a complementary aid for cancer patients. Its advanced extraction method ensures the preservation of active compounds, making it a valuable tool for maintaining health in modern life.